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28 Co-occurring conditions like anxiety, depression, stress, and sleep disorders can be contributors, while disturbances that are difficult to diagnose, such as dysregulated stress reactivity, neurotransmitter imbalance, inflammation, mitochondrial dysfunction, free radical damage, hormonal imbalance, and metabolic disturbance, as well as crosstalk between these factors, may also play a role

52 Furthermore, increased non-oxidative glucose utilisation was observed and was evidenced by an increase in plasma lactate concentrations

doi:10.1016/j.ijbiomac.2023.127127 20

Wang S, Chen B, Du R, Zhong M, Zhang C, Jin X et al (2024) An herbal formulation Shugan Xiaozhi decoction ameliorates methionine/choline deficiency-induced nonalcoholic steatohepatitis through regulating inflammation and apoptosis-related pathways